Repairing erosions in rheumatoid arthritis. A realistic goal
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چکیده
منابع مشابه
Remission: a realistic goal in rheumatoid arthritis?
Remission in randomized clinical trials The FIN-RACo study was the first randomized controlled rheumatoid arthritis (RA) trial that used remission as the primary outcome measure [1]. In the FIN-RACo trial, remission was defined as the treatment goal and the primary outcome measure as early as 1993, years before the first biologic agent became available. Results of FIN-RACo were amazing: 42% of ...
متن کاملRib erosions in rheumatoid arthritis.
Defects in the superior margin of ribs, of an erosive nature, appear to be uncommon, the chief causes being poliomyelitis (Bernstein, Loeser, and Manning, 1958), hyperparathyroidism (Noetzli and Steinbach, 1962), rheumatoid arthritis (Alpert and Feldman, 1964), scleroderma (Keats, 1967); other rarer causes have been summarized by Boone, Swenson, and Felson (1964), Gayler and Donner (1967), and ...
متن کاملHealing of erosions in rheumatoid arthritis.
Reports on healing of erosions in rheumatoid arthritis are rare. However, it is expected that repair of erosions should be seen more often during the period of extensive use of disease modifying antirheumatic drugs, especially in patients who experience sustained remission. Two such cases are described.
متن کاملLocal bone erosions in rheumatoid arthritis
Bone erosion is a hallmark of rheumatoid arthritis. Recent evidence from experimental arthritis suggests that osteoclasts are essential for the formation of local bone erosions. Two essential regulators of osteoclastogenesis have recently been described: the receptor-activator of nuclear factor kappa B ligand, which promotes osteoclast maturation, and osteoprotegerin (OPG), which blocks osteocl...
متن کاملMetabolic activity of erosions in rheumatoid arthritis.
The hands of 10 patients with rheumatoid arthritis were investigated with diphosphonate scanning and radiology. Increased uptake of isotope can be associated with some erosions but not all and also reflects other processes more linked to acute inflammatory areas unassociated with the development of erosions. If the latter are the hallmark of active rheumatoid arthritis then bone scans are not.
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2008
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/ken243